Richard Neher
i am a biologist/physicist at the @biozentrum in Basel trying to understand how microbes evolve. views are my own, RT!=endorsement.
Thought Leader
| #38 | Infectious Disease |
Last synced from Twitter 7h ago
The Coronavirus Is Mutating, and That’s Fine (So Far)
SARS-CoV-2 has been slowly changing in small ways, without getting more dangerous.
13
Richard Neher
"Viruses mutate constantly; SARS-CoV-2 is no different. And it’s essential that we continue to monitor when and how, and with what effects, it is evolving."
@edwardcholmes explains in the @nytimes why mutations of #SARSCoV2 are no reason for panic.
11d
40 Under 40: The Most Influential Young People in Business 2017
Read on to meet these disruptors, innovators, rebels and artists—and prepare to be inspired.
Zahlen & Fakten zu COVID-19
Analysen und Daten zu SARS-CoV-2 und COVID-19 sowie den sozialen und wirtschaftlichen Auswirkungen der Pandemie im Kanton Zürich und der Schweiz.
About SalivaDirect
Regularly testing large numbers of people will play a huge role in monitoring transmission of SARS-CoV-2. Quickly detecting and isolating active cases – people who can transmit the virus, whe…
Coronavirus (COVID-19) Update: FDA Issues Emergency Use Authorization to Yale School of Public Health for SalivaDirect, Which Uses a New Method of Saliva Sample Processing
The FDA issued an emergency use authorization to Yale School of Public Health for SalivaDirect, a COVID-19 diagnostic test, using a new method of processing sal
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with high attack rate
The development of vaccines against SARS-CoV-2 would be greatly facilitated by the identification of immunological correlates of protection in humans. However, to date, studies on protective immunity have only been performed in animal models and...
Eurosurveillance | Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020
We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all...
Potential impact of seasonal forcing on a SARS-CoV-2 pandemic
The authors explore how seasonal variation in transmissibility could modulate a SARS-CoV-2 pandemic. The likely aggregated effect of seasonal variation, infection control measures, and transmission rate variation is a prolonged pandemic wave with...
2
Richard Neher
Some background:
Our modeling study from February:
smw.ch/article/doi/sm…
A review of seasonal effects on respiratory viruses:
annualreviews.org/doi/10.1146/an…
40d
Seasonality of Respiratory Viral Infections
The seasonal cycle of respiratory viral diseases has been widely recognized for thousands of years, as annual epidemics of the common cold and influenza disease hit the human population like clockwork in the winter season in temperate regions....
2
Richard Neher
Some background:
Our modeling study from February:
smw.ch/article/doi/sm…
A review of seasonal effects on respiratory viruses:
annualreviews.org/doi/10.1146/an…
40d
About - Andersen Lab
Read more about the lab and potential jobs.
KITP
Richard Neher
Boris Shraiman at @KITP_UCSB is organizing a bacteriophage forum (weekly online seminar series) over the next few weeks. First session tomorrow at noon pacific, 15h east coast, 21h CEST
43d
SeroTracker: a global SARS-CoV-2 seroprevalence dashboard
As the initial phase of the COVID-19 pandemic passes its peak in many countries, serological
studies are becoming increasingly important in guiding public health responses. Antibody
testing is crucial for monitoring the evolution of the pandemic,...
SeroTracker
SeroTracker's serology testing dashboard monitors and visualizes SARS-CoV-2 seroprevalence studies.
3
Richard Neher
I am concerned that the #SARSCoV2 seroprevalence tracker at serotracker.com will mislead many.
55% in Italy or 14% in Germany are clearly wrong. These are estimates from hotspots generalized to entire countries. This caveat is only disclosed in a tiny pop-up. pic.twitter.com/tdtKf2EyZp
48d
Primi risultati dell'indagine di sieroprevalenza sul SARS-CoV-2
Online i primi risultati dell’indagine di sieroprevalenza a cura di Ministero della Salute e Istat
Zahl der Corona-Infizierten in Italien wohl deutlich höher
Als das neuartige Coronavirus im Frühjahr nach Europa kam, traf es Italien besonders hart. Jetzt haben Forscher untersucht, wie hoch die Dunkelziffer der Infizierten in dem Land ist - mit einem bemerkenswerten Ergebnis.
1
Richard Neher
Nonetheless, @tagesschau reports this as "way more infections than previously known". Nobody ever assumed Italy (or any country) caught all infections. Very poor reporting.
49d
Limited predictability of amino acid substitutions in seasonal influenza viruses
Seasonal influenza viruses repeatedly infect humans in part because they rapidly change their antigenic properties and evade host immune responses, necessitating frequent updates of the vaccine composition. Accurate predictions of strains...
17
Richard Neher
Pierre Barrat just posted a preprint on influenza virus evolution (with me @huddlej @trvrb).
Influenza escapes preexisting immunity by rapidly changing its surface proteins. You'd expect that mutations that come up quickly are beneficial and sweep [1/7]
biorxiv.org/content/10.110… pic.twitter.com/jjztUUhsLq
52d
Persistent heterogeneity not short-term overdispersion determines herd immunity to COVID-19
It has become increasingly clear that the COVID-19 epidemic is characterized by overdispersion whereby the majority of the transmission is driven by a minority of infected individuals. Such a strong departure from the homogeneity assumptions of...
Time is of the essence: containment of the SARS-CoV-2 epidemic in Switzerland from February to May 2020
AIM: In late February and early March 2020, Switzerland experienced rapid growth of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections with 30,243 confirmed cases and 1,860 deaths as of 10 May 2020. The sequential introduction...