Sanam Loghavi, MD
Hematopathologist/Molecular Pathologist #endcancer #hemepath #mpnsm #lymsm #leusm #hemepathMDA
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Pathpresenter.net 93d 1 tweets
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Sanam Loghavi, MD Need 2 take Ur mind off the #Election2020 frenzy for a min? Join me and in solving this #hemepath case. Elderly ♂️, referred 4 suspected acute leukemia. WBC:100 K/uL,Hb:13.2 g/dL,Plt:105, 94% "blasts" BM slides: What would U order next? 93d
Emergence of BCR–ABL1 Fusion in AML Post–FLT3 Inhibitor-Based Therapy: A Potentially Targetable Mechanism of Resistance – A Case Series
Frontiers 99d 2 tweets
Despite the promising result with FLT3 inhibitors in AML, the emergence of resistance poses a significant challenge, leading to a shorter response duration and inferior survival. This is frequently driven by on-target or parallel prosurvival...
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Sanam Loghavi, MD Emergence of BCR–ABL1 Fusion in AML Post–FLT3 Inhibitor-Based Therapy: A Potentially Targetable Mechanism of Resistance – A Case Series #hemepathMDA #leusm #hemepath 99d
A Cryptic BCR-PDGFRB Fusion Resulting in a Chronic Myeloid Neoplasm With Monocytosis and Eosinophilia: A Novel Finding With Treatment Implications
JNCCN 109d 2 tweets
<section class="abstract"><p>RNA-seq was used to identify the partner gene and confirm the presence of a <em>BCR-PDGFRB</em> fusion. Identification of this fusion product resulted in successful treatment and long-term remission of this myeloid...
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Sanam Loghavi, MD ➡️Just out in JNCCN: we describe a novel and cryptic BCR-PDGFRB fusion resulting in a chronic myeloid neoplasm with monocytosis and eosinophilia #leusm #mpnsm 109d
Mohammad Reza Shajarian: Tiny Desk Concert
NPR.org 110d 1 tweets
Joined by three excellent collaborators, Shajarian gives what amounts to a brief master class in the art of singing. In the course of this love song, titled "Az Eshgh," the Iranian icon unleashes torrents of swooping, soaring, goosebump-inducing...
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Sanam Loghavi, MD A truly sad day for all Iranians around the world as we mourn the loss of our greatest classical vocalist. May you #RIP and May your legacy and art carry on for generations. Mohammad Reza Shajarian: Tiny Desk Concert : NPR #shajarian #محمدرضا_شجریان 110d
ICCS Virtual Meeting
Cytometry.org 118d 1 tweets
Online Meeting Program
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Sanam Loghavi, MD Watch the recorded version of ⁦⁩ and ⁦⁦⁩ ‘s CART session for diagnostic pearls and pitfalls when evaluating pts post CART cell therapy Virtual Meeting #FlowICCS20 118d
vICCS 2020 | Virtual Meeting
Cytometry.org 119d 1 tweets
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Sanam Loghavi, MD Gearing up for another exciting day of #FlowICCS20 with Plenary sessions on CAR-T Cell therapy, T cell lymphoma, live workshops and more 🙌🏻 vICCS 2020 | Virtual Meeting 119d
Expression of CD56 defines a distinct subgroup in childhood T‐ALL with inferior outcome. Results of the ALL‐BFM 2000 trial
Wiley Online Library 120d 1 tweets
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.
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Sanam Loghavi, MD 120d
ICCS Virtual Meeting
Cytometry.org 120d 1 tweets
Online Meeting Program
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Sanam Loghavi, MD Dr. Fuda and I are going live with workshop #4: Identifying and analyzing uncommon cells @ 12:45 PM EST. Join us #FlowICCS20 #hemepath #hemepathMDA #FLowEdu 120d
ICCS Virtual Meeting
Cytometry.org 120d 1 tweets
Online Meeting Program
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Sanam Loghavi, MD #FlowICCS20 goes live in less than one hour. Join us for a full day of phenomenal talks and workshops: full program @ 120d
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes
Nature Medicine 176d 6 tweets
Clinical sequencing across a large prospective cohort of patients with myelodysplasic syndrome uncovers distinct associations between the mono- and biallelic states of TP53 and clinical presentation
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Sanam Loghavi, MD Welcome to #hemepathJC happy to be moderating tonight’s discussion w/ We’ll be discussing this landmark paper by & team recently out in on the implications of #TP53 allelic state in MDS #MDSSM 124d
Immunophenotypic differentiation patterns of normal hematopoiesis in human bone marrow: Reference patterns for age‐related changes and disease‐induced shifts
Wiley Online Library 134d 1 tweets
Background The abundance of monoclonal antibodies (mAb) and the routine use of quadruple stainings in flow cytometry allow stepwise analysis of bone marrow (BM) samples that are suspected for abnorm...
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Sanam Loghavi, MD Yes. Immature monocytes typically show dimmer CD13, more CD15 and less CD14 compared to mature forms. See this article the image shows a nice summary too. 134d
vICCS 2020 | Virtual Meeting
Cytometry.org 162d 7 tweets
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Sanam Loghavi, MD Register for #flowICCS20 for the latest educational material in flow cytometry I'll be presenting "What's in the Background? Identifying & Analyzing Uncommon Cells" Monday with Dr. Buddy Fuda & "How to approach a BM by flow in suspected MDS" Wednesday 146d
Clinicopathological characterization of chronic lymphocytic leukemia with MYD88 mutations: L265P and non-L265P mutations are associated with different features
Blood Cancer Journal 153d 2 tweets
MYD88 mutations in chronic lymphocytic leukemia (CLL) are not well characterized. Earlier reports yielded conflicting results in terms of clinicopathologic presentation and prognostic impact of MYD88 mutations in CLL patients. In addition, the...
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Sanam Loghavi, MD 👉Just out.. characterization of CLL/SLL with MYD88 mutations: L265P & non-L265P mutations are associated with different features #hemepathMDA #hemepath #lymsm #leusm 150d
Hematopoietic neoplasms with 9p24/JAK2 rearrangement: a multicenter study
Modern Pathology 152d 1 tweets
The purpose of this study is to examine hematopoietic neoplasms with 9p24/JAK2 rearrangement including neoplasms associated with t(8;9)(p22;p24)/PCM1-JAK2 fusion neoplasm as well as cases with translocations involving 9p24/JAK2 and other partner...
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Sanam Loghavi, MD Interestingly myeloid neoplasms w/ PCM1-JAK2 frequently show proliferations of early erythroblasts in BM & extramedullary sites, often a diagnostic clue, as published by Dr. Tang , et al. in #hemepathMDA 152d
Transformation to erythroblastic sarcoma from myeloid neoplasm with PCM1-JAK2 | Blood | American Society of Hematology
Ashpublications.org 152d 2 tweets
Catherine Luedke, Lindsay Rein; Transformation to erythroblastic sarcoma from myeloid neoplasm with PCM1-JAK2, Blood, Volume 136, Issue 9, 27 August 2020, Page
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Sanam Loghavi, MD Interesting case in the latest issue of showing a myeloid neoplasms with PCM1-JAK2 manifesting as extramedullary pure erythroid leukemia. #hemepath #leusm 152d
The Utility of Flow Cytometry in Establishing the Correct Diagnosis of a Rare Aggressive Lymphoma
Lablogatory 155d 2 tweets
Case history A 73 year old woman presented with shortness of breath and was found to have bilateral pleural effusions. She had a history of marginal zone B-Cell lymphoma involving the bone marrow, …
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Sanam Loghavi, MD Brought to you by the one and only The Utility of Flow Cytometry in Establishing the Correct Diagnosis of a Rare Aggressive Lymphoma via #hemepath #FlowEdu #hemepathMDA #Lablogatory 155d
Thirty‐three years later: Two distinct cases of acute lymphoblastic leukemia in one patient
Wiley Online Library 159d 1 tweets
Click on the article title to read more.
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Sanam Loghavi, MD Thirty‐three years later: Two distinct cases of acute lymphoblastic leukemia in one patient 159d
The PathPod Podcast
Pathpod.podbean.com 270d 11 tweets
A Pathology podcast for everyone....
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Sanam Loghavi, MD Out tmrw: the latest episode of #BeyondtheScope & I discuss her path to achieving academic success, her advice on developing fruitful mentor-mentee relationships, work-life balance, overcoming challenges of being a female physician & more! 173d
Cuplike nuclei (prominent nuclear invaginations) in acute myeloid leukemia are highly associated with FLT3 internal tandem duplication and NPM1 mutation - PubMed
PubMed 175d 1 tweets
Cuplike nuclei in AML were highly associated with the presence of NPM1 and FLT3-ITD mutations and with several clinicopathologic and immunophenotypic features. Recognition of the distinctive morphologic features of AML with cuplike nuclei may be...
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Sanam Loghavi, MD One of those leukemias that read the books.. a perfect example of Cup-like blasts... flow phenotype was CD34-, CD117+, HLA-DR- , which often raises concern for APL... This is a classic example of NPM1-mutated AML.. #hemepath #leusm 175d
The Power List 2020
The Pathologist 180d 14 tweets
You nominated and our expert judging panels deliberated – and now, we proudly showcase this diversity of talent in The Pathologist’s 2020 Power List.
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Sanam Loghavi, MD Congrats #PathPower20 honorees who strive 2 help patients, educate others &promote path! U inspire @01sth02 179d