There is a simple mathematical truth that would have caused alarm about the coronavirus pandemic if it had been more fully appreciated when it was first flagged up in reports from China in late
Simon Mead22 days of dither and delay on coronavirus that cost thousands of British lives. Good work getting the truth out there. This certainly one of our countries worst ever events in terms of government strategy. And science / medicine must take some blame.
Health and high quality care for all, <br />now and for future generations
Simon MeadStatistics » COVID-19 Daily Deaths the death data here is tabulated by date of death (unlike reports from press conference date death was reported) April 8 still peak death day in this dataset so more optimistic peak has passed
Mammalian prions are lethal pathogens composed of fibrillar assemblies of misfolded prion protein. Human prion diseases are rare and usually rapidly fatal neurodegenerative disorders, the most common being sporadic Creutzfeldt-Jakob disease (sCJD)....
Simon MeadGenome-wide association study identifies risk variants for sporadic Creutzfeldt-Jakob disease in STX6 and GAL3ST1 | medRxiv
Professor responsible for ‘reckless’ failure to properly oversee researchers
Simon MeadJohn Hardy chair of the review panel quoted here is a sound opinion and obviously must feel strongly to speak out like this. Tldr: good leaders would take the rap for serial and long term misdoings in their teams.
Simon MeadMore evidence of human-human disease transmission by amyloid beta prions resulting in symptomatic cerebral amyloid angiopathy. Three patients presented with haemorrhages due to early onset CAA following surgical procedures that used cadaveric dura mater
Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series
Simon MeadOur new paper (first author Carolin Koriath) on the use of gene panels tech to diagnose inherited dementia. We look at the effects of clinical syndrome, age and family history on finding a mutation in a largish series
Germline BRCA1 loss-of-function variants are associated with predisposition to early-onset breast and ovarian cancer; here the authors use CRISPR/Cas9 genome editing to functionally assess thousands of BRCA1 variants in order to facilitate the...