Yonatan Grad
Assistant Prof of Immunology & Infectious Diseases at Harvard TH Chan School of Public Health. Studying infectious diseases & how pathogens evolve and spread.
Thought Leader
| #38 | Infectious Disease |
Last synced from Twitter 2h ago
Handyfuge-LAMP: low-cost and electricity-free centrifugation for isothermal SARS-CoV-2 detection in saliva.
Point of care diagnostics for COVID-19 detection are vital to assess infection quickly and at the source so appropriate measures can be taken. The loop-mediated isothermal amplification (LAMP) assay has proven to be a reliable and simple protocol...
Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants
Sampling informed by pathogen genomic data may facilitate more efficient detection of novel antibiotic resistance than random sampling.
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Yonatan Grad
Congratulations to @allielh3 on publication of her final PhD paper in @eLife! "Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants" doi.org/10.7554/eLife.… -- and see associated Insight piece elifesciences.org/articles/59379
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Antibiotic Resistance: Genomics against gonorrhoea
Surveillance strategies based on whole genome sequencing could help with the early identification and detection of new forms of drug-resistant gonorrhoea.
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Yonatan Grad
Congratulations to @allielh3 on publication of her final PhD paper in @eLife! "Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants" doi.org/10.7554/eLife.… -- and see associated Insight piece elifesciences.org/articles/59379
8d
Surveillance testing of SARS-CoV-2
The COVID-19 pandemic has created a public health crisis. Because SARS-CoV-2 can spread from individuals with pre-symptomatic, symptomatic, and asymptomatic infections, the re-opening of societies and the control of virus spread will be facilitated...
Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study
These results suggest that most of the population of Geneva remained uninfected during
this wave of the pandemic, despite the high prevalence of COVID-19 in the region (5000
reported clinical cases over <2·5 months in the population of half a...
Ancient bacterial genomes reveal a formerly unknown diversity of Treponema pallidum strains in early modern Europe
Sexually transmitted (venereal) syphilis marked European history with a devastating epidemic at the end of the 15th century, and is currently re-emerging globally. Together with non-venereal treponemal diseases, like bejel and yaws, found in...
Effects of non-pharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study
The characteristics of SARS-CoV-2 mean that extreme measures are probably required
to bring the epidemic under control and to prevent very large numbers of deaths and
an excess of demand on hospital beds, especially those in ICUs.
Regarding the Death of George Floyd
Dear Harvard Chan School Community, “I can’t breathe.” That was George Floyd’s final plea before his life was taken by a police officer kneeling on his neck… the very same plea uttered by Eric Garn…
How COVID-19 Made a Harvard Epidemiologist Into a Public Ambassador for Science | News | The Harvard Crimson
“I got a call from the Prime Minister of Israel who just wanted to talk about what they were doing,” Marc Lipsitch said. “That's a level of advice that I've never been asked to do before and has been really interesting.”
LarremoreLab/bayesian-joint-prev-se-sp
Contribute to LarremoreLab/bayesian-joint-prev-se-sp development by creating an account on GitHub.
Jointly modeling prevalence, sensitivity and specificity for optimal sample allocation
The design and interpretation of prevalence studies rely on point estimates of the performance characteristics of the diagnostic test used. When the test characteristics are not well defined and a limited number of tests are available, such as...
Deep Background with Noah Feldman
Every story has a backstory, even in today's 24-hour news cycle. In Deep Background, Harvard Law School professor and Bloomberg View columnist Noah Feldman will bring together a cross-section of expert guests to explore the historical, scientific,...
Individual quarantine versus active monitoring of contacts for the mitigation of COVID-19: a modelling study
Our model highlights the urgent need for more data on the serial interval and the
extent of presymptomatic transmission to make data-driven policy decisions regarding
the cost–benefit comparisons of individual quarantine versus active monitoring...
PathoSPOT genomic surveillance reveals under the radar outbreaks of methicillin resistant S. aureus bloodstream infections
Whole genome sequencing (WGS) is increasingly used to map the spread and transmission dynamics of human pathogens, especially in nosocomial settings. A limiting factor for more widespread adoption of WGS for infection prevention practices is the...