Yonatan Grad
Assistant Prof of Immunology & Infectious Diseases at Harvard TH Chan School of Public Health. Studying infectious diseases & how pathogens evolve and spread.
Thought Leader
| #33 | Infectious Disease |
Last synced from Twitter 81d ago
Viral dynamics of SARS-CoV-2 infection and the predictive value of repeat testing
SARS-CoV-2 diagnostics that report viral RNA concentrations can be used to determine a patient's stage of infection, but this potential has not yet been realized due to a lack of prospective longitudinal data to calibrate such inferences. Here, we...
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Yonatan Grad
New preprint: Here we report quantitative prospective longitudinal testing from @nba players, staff and vendors & consider how these data can be used to improve diagnostic and surveillance testing algorithms. medrxiv.org/content/10.110… 1/n
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To Interpret the SARS-CoV-2 Test, Consider the Cycle Threshold Value
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Yonatan Grad
Ct values from PCR tests can, in theory, reveal a person’s progress through the stages of infection academic.oup.com/cid/advance-ar… @michaelrtom @michaelmina_lab 3/n
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Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae
The mechanisms underlying resistance of Neisseria gonorrhoeae to the antibiotic azithromycin are incompletely understood. Here, Ma et al. conduct a conditional genome-wide association study to identify new resistance mutations and experimentally...
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Yonatan Grad
Our paper using conditional GWAS to discover new antibiotic resistance determinants in Neisseria gonorrhoeae, here including experimental validation of the role of rplD variants in azithromycin resistance, now out. 1/n
86d
Welcome! You are invited to join a meeting: CCDD COVID-19 and Health Inequities Seminar Series . After registering, you will receive a confirmation email about joining the meeting.
Schedule of speakers:
9/24/20: Bonnielin Swenor, Director of the Johns Hopkins Disability Health Research Center and Associate Professor of Ophthalmology at the Johns Hopkins Bloomberg School of Public Health
10/1/20: Jarvis Chen, Research...
Discussion: What's driving the latest coronavirus surges?
Many health officials around the world are working to contain second waves of the coronavirus. As part of our regular series on the pandemic with Harvard's T.H. Chan School of Public Health, join us as we examine what's driving the latest wave of...
The Coronavirus Pandemic
Facebook Live Q&A with Yonatan Grad, Assistant Professor in the Department of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health Presented jointly by The Forum …
Rethinking Covid-19 Test Sensitivity — A Strategy for Containment | NEJM
Perspective from The New England Journal of Medicine — Rethinking Covid-19 Test Sensitivity — A Strategy for Containment
Projects & Presentations
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COVID-19 and Health Inequities: Seminar Series
Seminars take place weekly on Thursdays from 2:00 – 3:00pm ET between September 24 and October 22, 2020. The COVID-19 pandemic in the United States has disproportionately affected communities…
IDDjobs — Modelling the impact of new diagnostics and treatments on the spread of antimicrobial-resistant gonorrhoea in South Africa — Institute of Social and Preventive Medicine, University of Bern
Find infectious disease dynamics modelling jobs, studentships, and fellowships.
Model-informed COVID-19 vaccine prioritization strategies by age and serostatus
When a vaccine for COVID-19 becomes available, limited initial supply will raise the question of how to prioritize the available doses and thus underscores the need for transparent, evidence-based strategies that relate knowledge of, and uncertainty...
Potential Biases Arising from Epidemic Dynamics in Observational Seroprotection Studies
Abstract. The extent and duration of immunity following SARS-CoV-2 infection are critical outstanding questions about the epidemiology of this novel virus, and
High precision Neisseria gonorrhoeae variant and antimicrobial resistance calling from metagenomic Nanopore sequencing
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
The Impact of Pf Bacteriophages on the Fitness of Pseudomonas aeruginosa; A Mathematical Modeling Approach
Pseudomonas aeruginosa ( Pa ) is a major bacterial pathogen responsible for chronic lung infections in cystic fibrosis patients. Recent work by ourselves and others has implicated Pf bacteriophages, non-lytic filamentous viruses produced by Pa , in...
Smith Family Foundation: Odyssey Award - Health Resource in Action
The Smith Odyssey Award supports the pursuit of high impact ideas to generate breakthroughs and drive new directions in biomedical research.
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Yonatan Grad
Thanks so much to the Smith Family Foundation for the support through the Odyssey Award! The lab is looking for new post-docs, with official ads to post very soon -- interests & backgrounds in genomics, microbiology, and bioinformatics welcome!
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PrkC modulates MreB filament density and cellular growth rate by monitoring cell wall precursors
How bacteria link their rate of growth to the external nutrient conditions is not known. To explore how Bacillus subtilis modulates the rate cells expand their encapsulating cell wall, we compared the single-cell growth rate to the density of moving...
The rabbi who is neighbor to Mark and Patricia McCloskey speaks out: ‘They are bullies’
The rabbi who is neighbors to Mark and Patricia McCloskey speaks out: ‘They are bullies’
Jobs
Postdoc opportunity August 1, 2020 Nathan Grubaugh, Anne Wyllie, and Dan Weinberger at the Yale School of Public Health are hiring a joint postdoc to develop COVID-19 testing strategies and uncover…